FGFR2b NUGC4
CBP74672
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| I. Background | |
| FGFR2b（成纤维细胞生长因子受体2 IIIb亚型）是FGFR2基因顺利获得选择性剪接产生的一种受体变体，特异性地表达于上皮细胞，其配体为FGF7亚家族成员（FGF7、FGF10、FGF22）。它在胃癌、肝内胆管癌等多种实体瘤中高表达，是抗体药物（如Bemarituzumab）和ADC药物的重要靶点。 | |
| II. Description | |
| FGFR2b NUGC4细胞，在 NUGC4细胞的基础上，稳定表达 FGFR2b。 | |
| III. Introduction | |
| Expressed gene: | FGFR2b |
| Host Cell: | NUGC4 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant FGFR2b NUGC4 constitutively expressing FGFR2b. |
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