GPR6 HEK293
CBP71669
询 价
索取protocol
产品描述
产品数据库
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I. Background |
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| GPR6是一种A类孤儿G蛋白偶联受体，主要表达于大脑纹状体等区域，具有组成性激活特性，能持续升高细胞内cAMP水平。它参与调控神经元发育、运动行为和代谢过程，并与帕金森病相关的运动障碍有关。此外，GPR6也被发现是阿尔茨海默病模型中介导神经保护作用的早期反应蛋白之一。 | |
| II. Description | |
| GPR6 HEK293 药靶模型很好的模拟了体内 GPR6 的信号转导过程。 | |
| III. Introduction | |
| Expressed gene: |
GPR6
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| Host Cell: |
HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
DMEM+10%FBS+2 μg/ml Puromycin
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| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for GPR6 receptor |
| Transducer: | Gs |
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IV. Representative Data
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